Clyde Shelton (Gerard Butler) is an upstanding family man whose wife and daughter are brutally murdered during a home invasion. When the killers are caught, Nick Rice (Jamie Foxx), a hotshot young Philadelphia prosecutor, is assigned to the case. Over his objections, Nick is forced by his boss to offer one of the suspects a light sentence in exchange for testifying against his accomplice. Fast forward ten years. The man who got away with murder is found dead and Clyde Shelton admits his guilt. Then he issues a warning to Nick: Either fix the flawed justice system, or key players in the trial will die. Soon Shelton follows through on his threats, orchestrating from his jail cell a string of spectacularly diabolical assassinations that can be neither predicted nor prevented. Only Nick can stop the killing and finds himself in a desperate race against time facing a deadly adversary who seems always to be one step ahead.